ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Push! Pull! Push! Pull! / Highlights from Davos 2018
Lancet: 10-20-30 targets to address AMR by 2030
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
The 6 meanings of “Lack of Access” (UNSLAP)
The 37,000-year view: Infections in Eurasia
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
De-risking vaccine development: Insights spanning decades of experience
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
In Praise of Non-Inferiority
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet